Biography

Dr. Hofmeister has over 25 years of scientific leadership and a successful track record of drug discovery and early development. Since March 2022, he holds the CSO position at a stealth mode biotech company using their proprietary protein platform to revolutionize the treatment of multiple diseases. In this role, he drives development and indication strategy that leverages their novel therapeutic modality.

He joined TCR² Therapeutics in 2015 as the company’s first employee, serving as SVP, R&D before promotion to his most recent role of Chief Scientific Officer. There, he was instrumental in building and leading the R&D function and driving the development of their proprietary TRuC^®-T cell platform from concept to first cleared IND (TC-210 program). As part of senior leadership, he successfully contributed to taking the company public and securing multi-million dollar rounds of fundraising.

Previously, Dr. Hofmeister held various roles at EMD Serono where he was involved in the development of now approved Bavencio (avelumab) and building the company’s immuno-oncology platform. He started his biotech career at Micromet AG, now Amgen Research Munich, where he helped shape the development of Blincyto (blinatumomab), the first FDA-approved bispecific antibody for the treatment of refractory ALL.

Dr. Hofmeister received his Ph.D. from the University of Regensburg in Germany, where he studied the signaling of the cytokine interleukin-1. He continued to work in the cytokine field as a postdoctoral fellow at the National Cancer Institute.